Fmoc-β-Ala-Asp (OMpe) -OH
Fmoc-β-Ala-Asp (OMpe) -OH is a specialized amino acid derivative used in solid-phase peptide synthesis (SPPS) . Fmoc-β-Ala-Asp (OMpe) -OH consists of a beta-alanine spacer linked to an aspartic acid residue, where the beta-carboxyl group is protected with a 3-methylpentyl ester (OMpe) to prevent aspartimide formation during synthesis. Fmoc-β-Ala-Asp (OMpe) -OH a useful building block for creating peptides that contain aspartic acid, as the OMpe group is designed to minimize unwanted side reactions[1].
Product Specifications
UNSPSC
12352211
Target
Amino Acid Derivatives; Drug Intermediate
Related Pathways
Others
Field of Research
Others
Purity
97.63
Smiles
O=C(CCNC(OCC1C2=CC=CC=C2C3=CC=CC=C13)=O)N[C@H](C(O)=O)CC(OC(CC)(CC)C)=O
Molecular Formula
C28H34N2O7
Molecular Weight
510.58
References & Citations
[1]Mergler M, Dick F. The aspartimide problem in Fmoc-based SPPS. Part III. J Pept Sci. 2005 Oct;11 (10) :650-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
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