PSB-17365
PSB-17365 is a potent GPR84 agonist with EC50 values of 2.5 nM and 100 nM in a cAMP accumulation assay and a β-arrestin 2 recruitment assay, respectively[1].
Product Specifications
CAS Number
[2189700-03-4]
UNSPSC
12352005
Target
GPR84
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Smiles
O=C1C=C(NCCC2=CC=C(C=C2)Br)NC(N1)=O
Molecular Formula
C12H12BrN3O2
Molecular Weight
310.15
References & Citations
[1]Pillaiyar, T., et al., (2018) . 6- (Ar) Alkylamino-Substituted Uracil Derivatives: Lipid Mimetics with Potent Activity at the Orphan G Protein-Coupled Receptor 84 (GPR84) . ACS omega, 3 (3), 3365-3383.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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