JHU-58
JHU-58 is a peptidomimetic agonist targeting mouse MRGPRC11 and rat MRGPRC receptors. JHU-58 demonstrates analgesic effects in mouse models of neuropathic pain. JHU-58 is promising for research of neuropathic pain[1].
Product Specifications
CAS Number
[1632140-61-4]
UNSPSC
12352005
Target
Mas-related G-protein-coupled Receptor (MRGPR)
Related Pathways
GPCR/G Protein
Field of Research
Neurological Disease
Smiles
NC([C@H](CC1=CC=CC=C1)NC([C@H](N)CC2=CC=C(C=C2)NC(N)=N)=O)=O
Molecular Formula
C19H24N6O2
Molecular Weight
368.43
References & Citations
[1]Prchalová E, et al. Discovery of Benzamidine- and 1-Aminoisoquinoline-Based Human MAS-Related G-Protein-Coupled Receptor X1 (MRGPRX1) Agonists. J Med Chem. 2019 Sep 26;62 (18) :8631-8641.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-179458/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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