Apoptosis inducer 53
Apoptosis inducer 53 is an apoptosis inducer. Apoptosis inducer 53 can inhibit proliferation of human tumor cell lines (A549, HeLa, SW1573, T-47D, WiDr) with GI50 values of 2.5-9.1 μM. Apoptosis inducer 53 can induce cancer cells apoptosis and reduce colony formation. Apoptosis inducer 53 can activate p38α MAPK signaling and exerts anti-inflammatory effect. Apoptosis inducer 53 also shows anti-Leishmania donovani activity. Apoptosis inducer 53 can be used for the researches of cancer, infection and inflammation[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; p38 MAPK; Parasite
Related Pathways
Anti-infection; Apoptosis; MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Inflammation/Immunology
Smiles
O[C@H]1[C@H](OCC2=CC=C(F)C=C2)[C@@H](F)[C@@H](S(CCCCCCCCCCCC)(=O)=O)N3[C@@H]1COC3=O
Molecular Formula
C26H39F2NO6S
Molecular Weight
531.65
References & Citations
2
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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