Aromatase-IN-7
Aromatase-IN-7 (compound 75) is a potent and selective aromatase inhibitor (IC50 = 5.78 nM), exhibiting potency comparable to Letrozole. Aromatase-IN-7 exhibits potent aromatase inhibition both in vitro and in vivo. Aromatase-IN-7 can be used for hormone-dependent breast cancer (HDBC) research[1].
Product Specifications
UNSPSC
12352005
Target
Cytochrome P450
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
CN(C(S1)=O)C2=C1C=CC(C(C3=CC=C(C#N)C=C3)N4N=CN=C4)=C2
Molecular Formula
C18H13N5OS
Molecular Weight
347.39
References & Citations
[1]Park CH, et al. Functionalized nitrogen- and chalcogen-containing heterocyclic compounds as aromatase inhibitors: Design, synthesis and biological evaluation. Eur J Med Chem. 2026 Jan 15;302 (Pt 2) :118298.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Aromatase/CYP19A1
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