HP1-IN-2
HP1-IN-2 (Compound (R) -18) is a HP1/H3K9me3 interaction inhibitor with an IC50 of 18.1 μM. HP1-IN-2 can be used for studying various cancers with overexpression of HP1[1].
Product Specifications
CAS Number
[1385556-53-5]
UNSPSC
12352005
Target
Histone Methyltransferase
Related Pathways
Epigenetics
Field of Research
Cancer
Smiles
O=[N+]([O-])C1=CC=C(CN2[C@@H](C3=CC(OCCO4)=C4C=C3)CCC2)C=C1
Molecular Formula
C19H20N2O4
Molecular Weight
340.37
References & Citations
[1]Tokuyama A, et al. Identification of a novel small-molecule inhibitor of heterochromatin protein 1. Bioorg Med Chem Lett. 2026 Feb 1;131:130469.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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