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Anti-HIV agent 1

Anti-HIV agent 1 (compound 10i) is a potent antiviral agent with anti-HIV activity (IC50 = 10.6 nM) . anti-HIV agent 1 exhibits moderate to no inhibitory activity against RT mutant strains, but maintains their activity against wild-type viruses. anti-HIV agent 1 strongly shows dual inhibition of the viral attachment and reverse transcriptase phases of the viral life cycle. anti-HIV agent 1 can be used for HIV infection research[1].

Product Specifications

UNSPSC

12352005

Target

HIV

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

ClC1=CC=C(C=C1Cl)CNC(C2=NN=NN2C3CCCCC3)C4=CNC5=C4C=CC=C5

Molecular Formula

C23H24Cl2N6

Molecular Weight

455.38

References & Citations

[1]Mashaole T.C. Ragedi, et al. New 3-[ (tetrazol-5-yl) methine-N-benzylamine) ]-1H-indole derivatives: Synthesis, anti-HIV activity and molecular docking studies. European Journal of Medicinal Chemistry. 2026 (302) .

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HIV-1

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