Anti-HIV agent 1
Anti-HIV agent 1 (compound 10i) is a potent antiviral agent with anti-HIV activity (IC50 = 10.6 nM) . anti-HIV agent 1 exhibits moderate to no inhibitory activity against RT mutant strains, but maintains their activity against wild-type viruses. anti-HIV agent 1 strongly shows dual inhibition of the viral attachment and reverse transcriptase phases of the viral life cycle. anti-HIV agent 1 can be used for HIV infection research[1].
Product Specifications
UNSPSC
12352005
Target
HIV
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
ClC1=CC=C(C=C1Cl)CNC(C2=NN=NN2C3CCCCC3)C4=CNC5=C4C=CC=C5
Molecular Formula
C23H24Cl2N6
Molecular Weight
455.38
References & Citations
[1]Mashaole T.C. Ragedi, et al. New 3-[ (tetrazol-5-yl) methine-N-benzylamine) ]-1H-indole derivatives: Synthesis, anti-HIV activity and molecular docking studies. European Journal of Medicinal Chemistry. 2026 (302) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1
Curated Selection
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