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VDR ligand-1

VDR ligand-1 (compound 13a) is a nonsecosteroidal VDR agonist with an EC50 value of 16 nM. VDR ligand-1 can be used for osteoporosis, psoriasis, and cancer research[1].

Product Specifications

UNSPSC

12352100

Target

VD/VDR

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Cancer; Inflammation/Immunology; Metabolic Disease

Smiles

[H][C]1234[BH]567[BH]89%10[BH]%11%12%13[B]8%14%15(C%16=CC=C(OCC(O)=O)C=C%16)[BH]95%17[C]61%18(C%19=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C%19)[BH]%17%14%20[BH]%11%15%21[BH]%122([BH]%214%18%20)[BH]%10%1373

Molecular Formula

C19H22B10F6O4

Molecular Weight

536.48

References & Citations

[1]Mudiyanselage HNTN, et al. Design, synthesis and structural development of nonsecosteroidal VDR ligands based on the C, C'-diphenyl-m-carborane scaffold. Eur J Med Chem. 2026 Jan 15;302 (Pt 2) :118320.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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