HDAC6-IN-68
HDAC6-IN-68 is an HDAC6 inhibitor (IC50 = 118 nM) and a ligand for the target protein for PROTAC (HDAC6) . HDAC6-IN-68 can be used to synthesize PROTAC HDAC6 degrader 7 (HY-179421) [1].
Product Specifications
UNSPSC
12352005
Target
HDAC; Ligands for Target Protein for PROTAC
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; PROTAC
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=CC=C(CN2C3=CC=CC=C3C=CC4=C2C=CC=C4O)C=C1)NNCC
Molecular Formula
C24H23N3O2
Molecular Weight
385.46
References & Citations
[1]Sun S, et al. Design, Synthesis, and Anti-inflammatory Activity Evaluation for Hydrazide-Based HDAC6 Targeted Protein Degraders. J Med Chem. 2025 Nov 27;68 (22) :24519-24545.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC6
Curated Selection
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