Galectin-3-IN-7
Galectin-3-IN-7 is a selective Galectin-3 inhibitor with a Kd of 5.7 nM and shows 390-fold selectivity over Gal-1. Galectin-3-IN-7 can downregulate profibrotic signaling such as ACTA2, COL1A2, and FN1 in TGFβ-stimulated LX2 hepatic stellate cells. Galectin-3-IN-7 can be used for the research of fibrosis[1].
Product Specifications
UNSPSC
12352005
Target
Galectin
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Others
Smiles
O=C(C1=CC2=C(C(N([C@H]3[C@H](O)[C@@H](O)[C@H](S[C@H]4[C@H](O)[C@@H](N5N=NC(C6=CC=CC(F)=C6)=C5)[C@@H](O)[C@@H](CO)O4)[C@@H](CO)O3)C(C)=O)=C1)C=CN2)O
Molecular Formula
C31H34FN5O11S
Molecular Weight
703.69
References & Citations
NN
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Galectin-3
Curated Selection
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