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β-catenin-IN-9

β-catenin-IN-9 is a β-catenin inhibitor. β-catenin-IN-9 induces apoptosis, cell cycle arrest, and inhibits migration, invasion, and epithelial-mesenchymal transition (EMT) in colorectal cancer cells. β-catenin-IN-9 suppresses the transcription of β-catenin and vimentin, and significantly inhibits β-catenin at the protein level. β-catenin-IN-9 can be used for the research of colorectal cancer[1].

Product Specifications

CAS Number

3029462-00-5

UNSPSC

12352005

Target

Apoptosis; β-catenin

Related Pathways

Apoptosis; Stem Cell/Wnt

Field of Research

Cancer

Smiles

CCCCCCCCCCCCCCCCCC1=NN=C(SCN2CCOCC2)N1/N=C/C3=CN(CC4=CC=CC=C4)C5=C3C=CC=C5

Molecular Formula

C40H58N6OS

Molecular Weight

670.99

References & Citations

[1]Abdelmegeed H, et al. A novel 1,2,4-triazole derivative inhibits epithelial-mesenchymal transition in metastatic colorectal cancer via β-catenin suppression. Eur J Med Chem. 2026;302 (Pt 1) :118279.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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