Keap1-Nrf2-IN-29

Keap1-Nrf2-IN-29 (Compound 1a), a Curcumin (HY-N0005) analog, is a Keap1 protein inhibitor. Keap1-Nrf2-IN-29 exhibits significant inhibitory activity against A549, PC-3 and MCF-7 cells. Keap1-Nrf2-IN-29 can be used for the study of prostate cancer[1].

Product Specifications

UNSPSC

12352005

Target

Keap1-Nrf2

Related Pathways

NF-κB

Field of Research

Cancer

Smiles

[][Fe][].COC1=C(OC)C=CC(/C=C2CN(C)C/C(C\2=O)=C\c3cccc3)=C1.c4cccc4

Molecular Formula

C26H27FeNO3

Molecular Weight

457.34

References & Citations

[1]Seongjin Kim, et al. Targeting virulence to disarm the pathogen: Enzyme-activated-substrate inhibition of Anthrax edema factor. Volume 129, 15 December 2025, 130393