Telomerase-IN-9
Telomerase-IN-9 is a potent and selective telomerase inhibitor. Telomerase-IN-9 significantly reduces telomerase activity by binding to hTERT, leading to decreased telomerase function. Telomerase-IN-9 induces apoptosis and inhibits colony formation. Telomerase-IN-9 reduces tumor burden, restores antioxidantbalance, and preserves lung architecture in a Benzo[a]pyrene -induced lung cancer mouse model. Telomerase-IN-9 can be used for the research of lung cancer[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; Telomerase
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
COC1=CC2C(NC3=NN=C(C4=CC=CC=C4)S3)C5=CC=CC=C5NC2C=C1
Molecular Formula
C22H20N4OS
Molecular Weight
388.49
References & Citations
[1]Vishwakarma K, et al. Targeting telomerase for lung cancer: design and synthesis of acridine hybrids with in vitro and in vivo evaluation. Bioorg Med Chem Lett. 2026;131:130465.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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