BCL6 ligand-8
BCL6 ligand-8 is a PROTAC target protein ligand that can be used for synthesis of PROTACs, such as BCL6-760 (HY-178777) . BCL6-760 is a potent BCL6 PROTAC degrader with anti-tumor activity[1].
Product Specifications
CAS Number
[3084697-86-6]
UNSPSC
12352005
Target
BCL6; Ligands for Target Protein for PROTAC
Related Pathways
Immunology/Inflammation; PROTAC
Field of Research
Cancer
Smiles
CN(C(N(C1=C2)CCC(C)(O)C)=O)C1=CC=C2NC(N=C(F)N=C3)=C3Cl
Molecular Formula
C17H19ClFN5O2
Molecular Weight
379.82
References & Citations
[1]Shunatona HP, et al. Discovery of Potent and Selective BCL6 Ligand-Directed Degrader (LDD), BCL6-760. J Med Chem. 2025 Oct 23;68 (20) :21502-21519.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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