CBM-4077
CBM-4077 is a PROTAC E3 ligand that can be used for synthesis of PROTACs, such as BCL6-760 (HY-178777) . BCL6-760 is a potent BCL6 PROTAC degrader with anti-tumor activity[1].
Product Specifications
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(C(CC1)C2=NN(C)C3=C2C=CC(NC(CC4)CCN4C5=NC=CC=N5)=C3)NC1=O
Molecular Formula
C22H25N7O2
Molecular Weight
419.48
References & Citations
[1]Shunatona HP, et al. Discovery of Potent and Selective BCL6 Ligand-Directed Degrader (LDD), BCL6-760. J Med Chem. 2025 Oct 23;68 (20) :21502-21519.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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