DNPH1 ligand-1
DNPH1 ligand-1 (Compound 58) is a DNPH1 ligand. DNPH1 ligand-1 can be used as a target protein ligand (Ligands for Target Protein for PROTAC) for the development and design of PROTAC DNPH1 degraders. DNPH1 ligand-1 can be used to synthesize PROTAC DNPH1 Degrader 1 (HY-179582) [1].
Product Specifications
UNSPSC
12352005
Target
Glycosidase; Ligands for Target Protein for PROTAC
Related Pathways
Metabolic Enzyme/Protease; PROTAC
Field of Research
Cancer
Smiles
FC(F)(F)C1=CC(C2=CC(C(O)=O)=CC=C2NC3=NC(NC)=C4C(C=CC(OC5=CC=C(C=C5)C=O)=C4)=N3)=CC=C1
Molecular Formula
C30H21F3N4O4
Molecular Weight
558.51
References & Citations
[1]Anderson NA, et al. Use of Direct-to-Biology Strategies for the Discovery of 2'-Deoxynucleoside 5'-Monophosphate N-Glycosidase (DNPH1) PROTACs. J Med Chem. 2025 Nov 13;68 (21) :23421-23447.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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