USP1-IN-14
USP1-IN-14 (compound 27) is a ubiquitin-specific protease 1 (USP1) inhibitor with an IC50 of 0.001 µM. USP1-IN-14 can be used for USP1-related cancers, autoimmune and inflammatory disorders research[1].
Product Specifications
CAS Number
[3084277-96-0]
UNSPSC
12352005
Target
Deubiquitinase
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Cancer; Inflammation/Immunology
Smiles
COC1=C(C2=NC(C=CC=N3)=C3C(O[C@@H](C4=CC=C(C5=NC(C(F)(F)F)=CN5C(C)C)C=C4)C)=N2)C(C6CC6)=NC=N1
Molecular Formula
C30H28F3N7O2
Molecular Weight
575.58
References & Citations
[1]Hoyle DE, et al. Design and Synthesis of Novel USP1 Inhibitors for Therapeutic Applications. ACS Med Chem Lett. 2025 Oct 30;16 (11) :2197-2199.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
USP1
Curated Selection
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