SDH-IN-42
SDH-IN-42 (Compound D28) is a SDH (IC50: 5.38 μg/mL) inhibitor and antifungal agent. SDH-IN-42 exerts antifungal activity against R. solani by disrupting mycelial morphology, increasing cell membrane permeability, inducing the production and accumulation of ROS, and impairing mitochondrial function[1].
Product Specifications
UNSPSC
12352005
Target
Fungal; Mitochondrial Metabolism; Reactive Oxygen Species (ROS)
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C(C1=NOC(/C=C/C2=C(C)CCCC2(C)C)=C1)NNC3=CC=C(F)C(F)=C3
Molecular Formula
C21H23F2N3O2
Molecular Weight
387.42
References & Citations
[1]Su S, et al. Novel β-Ionone Derivatives Containing Isoxazole Hydrazide Moiety: Design, Synthesis, Antifungal Activity, and Action Mechanism. J Agric Food Chem. 2025 Nov 12;73 (45) :29160-29170.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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