PTP1B-IN-32
PTP1B-IN-32 (Compound 5G) is an uncompetitive PTP1B inhibitor, with a Ki value of 0.72 μM. PTP1B-IN-32 enhances insulin sensitivity. PTP1B-IN-32 can be used in the research of diabetes[1].
Product Specifications
CAS Number
2701546-87-2
UNSPSC
12352005
Target
Phosphatase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
C[C@]1(C(O)=O)CC[C@@]2(C)[C@@](C([C@@]3(C)CC2)=CC([C@@]4([H])[C@@]3(C)CC[C@]5([H])[C@]4(C)CC(C=NN6C7=CC=C(S(=O)(N)=O)C=C7)=C6C5(C)C)=O)([H])C1
Molecular Formula
C37H49N3O5S
Molecular Weight
647.87
References & Citations
[1]López-Sánchez M, et al. Optimization of Indole-and Pyrazole-fused Glycyrrhetinic Acid Derivatives as Potent PTP1B Inhibitors: In Silico, In Vitro, In Vivo, and Metabolomic Studies[J]. ACS Bio & Med Chem Au, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC043647-100 1x 100 µL
Spectrin beta III (SPTBN2) (rSPTBN2/1778), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
