PTP1B-IN-32
PTP1B-IN-32 (Compound 5G) is an uncompetitive PTP1B inhibitor, with a Ki value of 0.72 μM. PTP1B-IN-32 enhances insulin sensitivity. PTP1B-IN-32 can be used in the research of diabetes[1].
Product Specifications
CAS Number
2701546-87-2
UNSPSC
12352005
Target
Phosphatase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
C[C@]1(C(O)=O)CC[C@@]2(C)[C@@](C([C@@]3(C)CC2)=CC([C@@]4([H])[C@@]3(C)CC[C@]5([H])[C@]4(C)CC(C=NN6C7=CC=C(S(=O)(N)=O)C=C7)=C6C5(C)C)=O)([H])C1
Molecular Formula
C37H49N3O5S
Molecular Weight
647.87
References & Citations
[1]López-Sánchez M, et al. Optimization of Indole-and Pyrazole-fused Glycyrrhetinic Acid Derivatives as Potent PTP1B Inhibitors: In Silico, In Vitro, In Vivo, and Metabolomic Studies[J]. ACS Bio & Med Chem Au, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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