TAK-500 drug-linker
TAK-500 drug-linker is a drug-linker complex consisting of the STING protein agonist Dazostinag and a linker (HY-179279). TAK-500 drug-linker can be used to synthesize ADCs[1].
Product Specifications
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC; STING
Related Pathways
Antibody-drug Conjugate/ADC Related; Immunology/Inflammation
Field of Research
Others
Smiles
F[C@@H]1[C@H](O[P@](S)(OC[C@H]2[C@@H](O)[C@@H](O3)[C@H](N4C(N=CNC5=O)=C5C(F)=C4)O2)=O)[C@@H](CO[P@]3(S)=O)O[C@H]1N6C7=NC=NC(NC(C8=CC=CC=C8CN(C)C(OCC9=CC=C(NC([C@H](C)NC([C@H](C(C)C)NC([C@@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOC)=O)CCCCCN%10C(C=CC%10=O)=O)=O)=O)=O)C=C9)=O)=O)=C7N=C6
Molecular Formula
C75H100F2N14O27P2S2
Molecular Weight
1793.75
References & Citations
[1]Lee HM, et al. Identification of a Novel Linker Enabling the Bioconjugation of a Cyclic Dinucleotide for the STING Antibody-Drug Conjugate TAK-500. Bioconjug Chem. 2025 Nov 19;36 (11) :2423-2435.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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