TLR7 agonist 33
TLR7 agonist 33 (Compound 141) is a potent TLR7 activator with an EC50 of 1 nM. TLR7 agonist 33 can be used for cancer research[1].
Product Specifications
CAS Number
3099165-43-9
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
NC1=NC(N[C@H](CCO)CCC)=C(N(CC2=C(OC)C=CC(CNCC#N)=C2)C3=C4C=CC=C3)C4=N1
Molecular Formula
C27H33N7O2
Molecular Weight
487.60
References & Citations
[1]Sabnis RW. Novel Tricyclic Compounds as TLR7 Agonists for Treating Cancer. ACS Med Chem Lett. 2025 Oct 28;16 (11) :2208-2209.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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