SARS-CoV-2 nsp14-IN-9
SARS-CoV-2 nsp14-IN-9 (Compound 4P) is a selective nsp14 inhibitor with an IC50 of 0.20 μM. SARS-CoV-2 nsp14-IN-9 inhibits both mouse hepatitis virus and SARS-CoV-2 replication[1].
Product Specifications
UNSPSC
12352005
Target
SARS-CoV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
NC1=C2N=CN([C@H]3[C@H](O)[C@H](O)[C@@H](CSCC4=CC=C5C=CC=CC5=C4Br)O3)C2=NC=N1
Molecular Formula
C21H20BrN5O3S
Molecular Weight
502.38
References & Citations
[1]Rosas-Lemus M, et al. S-Adenosylhomocysteine Analogs Selectively Suppress Pan-Coronavirus Replication by Inhibition of nsp14 Methyltransferase. ACS Medicinal Chemistry Letters, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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