D-CAM-14

D-CAM-14 is a potent HBV capsid assembly modulator with potent anti-HBV activity (EC50 = 0.1 nM, EC90 = 9 nM in HepAD38 cells) . D-CAM-14 suppresses HBeAg, and HBcAg in HBV-infected HepG2-NTCP cells, with EC50 values of 98 and 67 nM, respectively. D-CAM-14 has distinct impacts on capsid radii and the morphology of preassembled capsids. D-CAM-14 can be used for HBV infection disease research[1].

Product Specifications

UNSPSC

12352005

Target

HBV

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

O=C(C(C1=C(N(C(C(NC2=CC(F)=C(C=C2)F)=O)=C1C)C)C)=O)NCC(N=N3)=CN3CCCCCCCCCCCCCCN(N=N4)C=C4CNC(C(C(N(C(C)=C5C(NC6=CC(F)=C(C=C6)F)=O)C)=C5C)=O)=O

Molecular Formula

C52H62F4N12O6

Molecular Weight

1027.12

References & Citations

[1]Amblard F, et al. Novel Dimeric Capsid Assembly Modulators as a Unique Class of Highly Potent Anti-HBV Agents. J Med Chem. 2025 Nov 27;68 (22) :24196-24212.