D-CAM-14
D-CAM-14 is a potent HBV capsid assembly modulator with potent anti-HBV activity (EC50 = 0.1 nM, EC90 = 9 nM in HepAD38 cells) . D-CAM-14 suppresses HBeAg, and HBcAg in HBV-infected HepG2-NTCP cells, with EC50 values of 98 and 67 nM, respectively. D-CAM-14 has distinct impacts on capsid radii and the morphology of preassembled capsids. D-CAM-14 can be used for HBV infection disease research[1].
Product Specifications
UNSPSC
12352005
Target
HBV
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O=C(C(C1=C(N(C(C(NC2=CC(F)=C(C=C2)F)=O)=C1C)C)C)=O)NCC(N=N3)=CN3CCCCCCCCCCCCCCN(N=N4)C=C4CNC(C(C(N(C(C)=C5C(NC6=CC(F)=C(C=C6)F)=O)C)=C5C)=O)=O
Molecular Formula
C52H62F4N12O6
Molecular Weight
1027.12
References & Citations
[1]Amblard F, et al. Novel Dimeric Capsid Assembly Modulators as a Unique Class of Highly Potent Anti-HBV Agents. J Med Chem. 2025 Nov 27;68 (22) :24196-24212.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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