P97-IN-2
P97-IN-2 is a p97 ATPase (IC50 = 0.6 μM) inhibitor. p97-IN-2 can inhibit cell proliferation, such as HCT15 (IC50 = 1.1 μM) and SW403 (IC50 = 0.8 μM) cells. p97-IN-2 can be used for cancer research[1].
Product Specifications
CAS Number
[1346527-45-4]
UNSPSC
12352005
Target
P97
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
COC1=CC=CC2=C1N=C(NCC3=CC=CC=C3)N=C2NCC4=CC=CC=C4
Molecular Formula
C23H22N4O
Molecular Weight
370.45
References & Citations
[1]Chou TF, et al. Structure-activity relationship study reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPase. ChemMedChem. 2013 Feb;8 (2) :297-312.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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