KRAS-IN-47
KRAS-IN-47 (Example 28) is a KRAS inhibitor with IC50 KRAS G12V. KRAS-IN-47 can be used for the study of cancers[1].
Product Specifications
CAS Number
3079342-05-2
UNSPSC
12352005
Target
Ras
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
FC1=C(C2=CC(N)=CC3=C2C(C#C)=C(F)C(F)=C3)N=CC4=C1N=C(N=C4N5[C@@]6([H])[C@](COCC5)([H])[C@@H]6F)OC([2H])([2H])[C@@]78N(CCC8)C[C@@H](C7)F
Molecular Formula
C33H27D2F5N6O2
Molecular Weight
638.63
References & Citations
[1]Michael David Bartberger, et al. Kras modulators. WO2025064542
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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