RIPK1-IN-37-CO-Ph-alkynyl-Py-Pip
RIPK1-IN-37-CO-Ph-alkynyl-Py-Pip is a Ligand-Linker conjunction, targeting RIPK1. RIPK1-IN-37-CO-Ph-alkynyl-Py-Pip can be used to synthesize PROTAC LD5097 (HY-179234) [1].
Product Specifications
UNSPSC
12352005
Target
Target Protein Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(N1CCC2=C1C=CC(C3=CN(C4=NC=NC(N)=C34)C5CCN(CC5)C(C6=CC=C(C=C6)C#CC7=CN=C(C=C7)N8CCNCC8)=O)=C2)CC9=CC=CC(OC(F)(F)F)=C9
Molecular Formula
C46H42F3N9O3
Molecular Weight
825.88
References & Citations
[1]Lu D, et al. Design, Optimization, and Development of RIPK1 Degraders with Improved Pharmacokinetic and Pharmacodynamic Properties. J Med Chem. 2025 Nov 13;68 (21) :22246-22263.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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