Pip-Py-alkynyl-Ph-COOH
Pip-Py-alkynyl-Ph-COOH is a PROTAC linker that can be used for the synthesis of PROTACs, such as LD5097 (HY-179234) . LD5097 is a potent RIPK1 PROTAC degrader with anti-tumor activity[1].
Product Specifications
UNSPSC
12352005
Target
PROTAC Linkers
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(O)C1=CC=C(C=C1)C#CC2=CN=C(C=C2)N3CCNCC3
Molecular Formula
C18H17N3O2
Molecular Weight
307.35
References & Citations
[1]Lu D, et al. Design, Optimization, and Development of RIPK1 Degraders with Improved Pharmacokinetic and Pharmacodynamic Properties. J Med Chem. 2025 Nov 13;68 (21) :22246-22263.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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