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Pip-Py-alkynyl-Ph-COOH

Pip-Py-alkynyl-Ph-COOH is a PROTAC linker that can be used for the synthesis of PROTACs, such as LD5097. LD5097 is a potent RIPK1 PROTAC degrader with anti-tumor activity[1].

Product Specifications

UNSPSC

12352005

Target

PROTAC Linkers

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C(O)C1=CC=C(C=C1)C#CC2=CN=C(C=C2)N3CCNCC3

Molecular Formula

C18H17N3O2

Molecular Weight

307.35

References & Citations

[1]Lu D, et al. Design, Optimization, and Development of RIPK1 Degraders with Improved Pharmacokinetic and Pharmacodynamic Properties. J Med Chem. 2025 Nov 13;68 (21) :22246-22263.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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