RIPK1-IN-37

RIPK1-IN-37 is an RIPK1 inhibitor and a ligand for the target protein for PROTAC (LD5097) . RIPK1-IN-37 can be used to synthesize PROTAC LD5097 (HY-179234) [1].

Product Specifications

CAS Number

[2782024-39-7]

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC; RIP kinase

Related Pathways

Apoptosis; PROTAC

Field of Research

Cancer

Smiles

O=C(N1CCC2=C1C=CC(C3=CN(C4=NC=NC(N)=C34)C5CCNCC5)=C2)CC6=CC=CC(OC(F)(F)F)=C6

Molecular Formula

C28H27F3N6O2

Molecular Weight

536.55

References & Citations

[1]Lu D, et al. Design, Optimization, and Development of RIPK1 Degraders with Improved Pharmacokinetic and Pharmacodynamic Properties. J Med Chem. 2025 Nov 13;68 (21) :22246-22263.