RIPK1-IN-37
RIPK1-IN-37 is an RIPK1 inhibitor and a ligand for the target protein for PROTAC (LD5097) . RIPK1-IN-37 can be used to synthesize PROTAC LD5097 (HY-179234) [1].
Product Specifications
CAS Number
[2782024-39-7]
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; RIP kinase
Related Pathways
Apoptosis; PROTAC
Field of Research
Cancer
Smiles
O=C(N1CCC2=C1C=CC(C3=CN(C4=NC=NC(N)=C34)C5CCNCC5)=C2)CC6=CC=CC(OC(F)(F)F)=C6
Molecular Formula
C28H27F3N6O2
Molecular Weight
536.55
References & Citations
[1]Lu D, et al. Design, Optimization, and Development of RIPK1 Degraders with Improved Pharmacokinetic and Pharmacodynamic Properties. J Med Chem. 2025 Nov 13;68 (21) :22246-22263.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
RIPK1
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