Deoxy-thalidomide-OMe
Deoxy-thalidomide-OMe is an E3 ligase ligand. Deoxy-thalidomide-OMe can be used for synthesis of PROTAC LRRK2 Degrader-4 (HY-178796) [1].
Product Specifications
CAS Number
[1061605-49-9]
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
COC1=CC=CC2=C1CN(C2=O)C3CCC(NC3=O)=O
Molecular Formula
C14H14N2O4
Molecular Weight
274.27
References & Citations
[1]Renner A C, et al. LRRK2 Degraders for Parkinson’s Disease and Inflammation: Tau and α-Synuclein Degraders for Neurodegeneration[J]. ACS Medicinal Chemistry Letters, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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