TLR9-IN-2
TLR9-IN-2 (Compound 20) is a selective inhibitor of Toll-like receptor 9 (TLR9) with IC50 values for TLR9, TLR7, and TLR8 of 25, 1400, and > 50,000 nM respectively. TLR9-IN-2 can be used for the study of fibrosis, autoimmune and inflammatory diseases[1].
Product Specifications
CAS Number
[2972638-16-5]
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
O=S(C(C=C1)=CC=C1C2=NC3=C(C)C=C(C4CCN(C5CCN(C(C)C)CC5)CC4)N=C3N2C)(C)=O
Molecular Formula
C28H39N5O2S
Molecular Weight
509.71
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR7; TLR8; TLR9
Curated Selection
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