N-Demethylonalespib
N-Demethylonalespib is a ligand for E3 ligase. N-Demethylonalespib can be used for synthesis of DDO3602 (HY-178496) [1].
Product Specifications
CAS Number
[2355276-57-0]
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(N1CC2=C(C=C(CN3CCNCC3)C=C2)C1)C4=CC(C(C)C)=C(O)C=C4O
Molecular Formula
C23H29N3O3
Molecular Weight
395.49
References & Citations
[1]Liu W, et al. HSP90 Mediates Targeted Degradation of Nonclient Protein PARP1 for Breast Cancer Treatment. J Med Chem. 2025 Oct 9;68 (19) :19933-19954.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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