PD-1/PD-L1-IN-59
PD-1/PD-L1-IN-59 (Compound MZ51) is a PD-1/PD-L1 inhibitor with an IC50 of 183 nM. PD-1/PD-L1-IN-59 can be used for the study of triple-negative breast cancer (TNBC) [1].
Product Specifications
CAS Number
[2891831-40-4]
UNSPSC
12352005
Target
PD-1/PD-L1
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Smiles
O=C1OC2=CC=CC=C2C(OC3=C(C=CC(OCC4=C(C(C5=CC=CC=C5)=CC=C4)C)=C3)CN6[C@@H](C[C@H](C6)O)C(O)=O)=C1
Molecular Formula
C35H31NO7
Molecular Weight
577.62
References & Citations
[1]Zhang M, et al. Molecular hybridization used to design and synthesize neo-tanshinlactone derivatives as PD-1/PD-L1 inhibitors. Bioorg Med Chem. 2022 Jan 15;54:116579.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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