SEH-H ligand 2
SEH-H ligand 2 is an sEH inhibitor and a ligand for the target protein for PROTAC (sEH). sEH-H ligand 2 can be used to synthesize PROTAC sEH-degrader-4.
Product Specifications
UNSPSC
12352005
Target
Epoxide Hydrolase; Ligands for Target Protein for PROTAC
Related Pathways
Metabolic Enzyme/Protease; PROTAC
Field of Research
Inflammation/Immunology
Smiles
O=C(NCCCC#C)C1=CC=C(O[C@H]2CC[C@H](NC(NC3=CC=C(OC(F)(F)F)C=C3)=O)CC2)C=C1
Molecular Formula
C26H28F3N3O4
Molecular Weight
503.51
References & Citations
[1]Schönfeld J, et al. Click chemistry enables rapid development of potent sEH PROTACs using a direct-to-biology approach. Chem Commun (Camb) . 2025 Nov 13;61 (92) :18108-18111.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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