K2V-9

K2V-9 is an AChE and MAO-B inhibitor with IC50 values of 1.72 μM and 0.950 μM against AChE and MAO-B, respectively. K2V-9 inhibits amyloid β self-aggregation and reduces ROS. K2V-9 has neuroprotective effects[1].

Product Specifications

UNSPSC

12352005

Target

Cholinesterase (ChE) ; Monoamine Oxidase

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Smiles

FC(C=C1)=CC=C1C2=NC(C3=CC=CC(OCC#C)=C3)=C(CCC4=C5C=CC=C4)C5=N2

Molecular Formula

C27H19FN2O

Molecular Weight

406.45

References & Citations

[1]Jangid K, et al. Investigation of the multifunctional profile of dihydroquinazoline derivatives as potential therapeutics for Alzheimer's disease. RSC Med Chem. 2025 Sep 17.