Gαq/11 protein-IN-2
Gαq/11 protein-IN-2 (Compound 9g) is a Gαq/11 protein inhibitor, with an IC50 of 11.3 μM. Gαq/11 protein-IN-2 induces Apoptosis, increases p-YAP. Gαq/11 protein-IN-2 has anticancer activity against uveal melanoma[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; P2Y Receptor; YAP
Related Pathways
Apoptosis; GPCR/G Protein; Stem Cell/Wnt
Field of Research
Cancer
Smiles
CCCCC(N1)=NC2=C1C(CC3CCCCC3)N(C([C@@H](N)[C@@H](C)CC)=O)CC2
Molecular Formula
C23H40N4O
Molecular Weight
388.59
References & Citations
[1]Hu Q L, et al. Chemoselective Minisci alkylation in aqueous medium: a general strategy for functionalization of complex N-heteroarenes and biomolecules. Green Chemistry, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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