Tubulin-IN-61
Tubulin-IN-61 is a tubulin polymerization inhibitor with an IC50 of ≤7.63 μM. Tubulin-IN-61 induces early apoptosis and triggers significant G2/M phase arrest. Tubulin-IN-61 elevates intracellular ROS levels. Tubulin-IN-61 shows high activity against MCF-7 cells with an IC50 of 5.61 μM. Tubulin-IN-61 can be used for the research of breast cancer[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; Microtubule/Tubulin; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
COC1=CC(C2=NC3=C(C=CC=C3)N2CC4=CN(N=N4)CC5=CC6=C(C(C7=CC=CS7)=N5)NC8=CC=CC=C86)=CC=C1OC
Molecular Formula
C34H27N7O2S
Molecular Weight
597.69
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-179160/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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