Tubulin-IN-60
Tubulin-IN-60 (Compound 4) is a tubulin polymerization inhibitor, with an IC50 of 0.19 μM. Tubulin-IN-60 has anti-cancer activity against colorectal, pancreatic, T-cell acute lymphoblastic leukemia cancer[1].
Product Specifications
UNSPSC
12352005
Target
Microtubule/Tubulin
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Cancer
Smiles
COC1=CC=C(C=C1)C2=CN(C=C2C(C3=CC(OC)=C(C(OC)=C3)OC)=O)C4=CC=CC=N4
Molecular Formula
C26H24N2O5
Molecular Weight
444.48
References & Citations
[1]Masci D, et al. Microwave-assisted synthesis of tubulin assembly inhibitors as anticancer agents by aryl ring reversal and conjunctive approach. RSC Med Chem. 2025 Jul 2;16 (10) :4845-4858.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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