α-Glucosidase-IN-101
α-Glucosidase-IN-101 (Compound 13j) is an uncompetitive α-glucosidase inhibitor, with an IC50 of 120 nM. α-Glucosidase-IN-101 properly inhibits CYP1A2, CYP2C19, and CYP2C9 isoforms of cytochrome P450. α-Glucosidase-IN-101 can be used in the research of diabetes[1].
Product Specifications
UNSPSC
12352005
Target
Cytochrome P450; Glycosidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
O=C(NC1=CC=C(Cl)C=C1)CN2N=NC(COC3=CC=C(/C=N/NC4=NC(C5=CC=CC=C5)=C(C6=CC=CC=C6)N=N4)C=C3)=C2
Molecular Formula
C33H26ClN9O2
Molecular Weight
616.07
References & Citations
[1]Asemanipoor N, et al. New 5,6-diphenyl-1,2,4-triazine-hydrazineylidene-phenoxy-1,2,3-triazole-acetamide derivatives as potent synthetic α-glucosidase inhibitors. RSC Adv. 2025 Oct 15;15 (46) :38547-38561.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CYP1; CYP2; Glucosidase
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