Siglec-7-IN-1
Siglec-7-IN-1 (Compound 8c) is a Siglec-7 inhibitor, with a Kd of 1.5 µM against Siglec-7-Fc. Siglec-7-IN-1 can be used in the research of cancer[1].
Product Specifications
UNSPSC
12352005
Target
Fc Receptor (FcR)
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Smiles
O=C(N[C@H](C(N1[C@H]2CCC1)=O)CCCNC(N)=N)[C@H](CSC3)NC([C@H](CC4=CNC5=C4C=CC=C5)NC(/C=N/OCCCCCCOC6=CC(CSC[C@H](NC([C@H](CC(N)=O)NC([C@@H](NC([C@H]([C@H](O)C)NC([C@H](C)NC2=O)=O)=O)C(C)C)=O)=O)C(N)=O)=CC3=C6)=O)=O
Molecular Formula
C60H86N16O14S2
Molecular Weight
1319.55
References & Citations
[1]Yazdan D, et al. Non-Carbohydrate Inhibitors of Sialic Acid-binding Immunomodulatory-type Lectin-7 (Siglec-7) Discovered from Genetically Encoded Bicyclic Peptide Libraries. bioRxiv, 2025: 2025.10. 10.681534.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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