TN-783
TN-783 is an orally active, brain-penetrant NLRP3 (IC50 = 19.3 nM) inhibitor. TN-783 enhances the effects of the GLP-1 receptor agonist semaglutide. TN-783 requires sustained targeted action, not permanent metabolic remodeling. TN-783 can be used for the study of obesity[1].
Product Specifications
CAS Number
2771021-30-6
UNSPSC
12352005
Target
NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation
Field of Research
Metabolic Disease; Inflammation/Immunology
Smiles
O=C(NC1=NC=C(C=N1)F)CN2C[C@H](C3=C(C2=O)C=CC(I)=C3)C(F)(F)F
Molecular Formula
C16H11F4IN4O2
Molecular Weight
494.18
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NLRP3
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog