Carbonic anhydrase-IN-36
Carbonic anhydrase-IN-36 (Compound 5p) is a MtCA 3 inhibitor with a Ki of 0.07 µM against MtCA 3. Carbonic anhydrase-IN-36 inhibits the β-class enzyme MtCA 3. Carbonic anhydrase-IN-36 demonstrates potent antimycobacterial activity, with an MIC of 8 µg/mL against Mtb. Carbonic anhydrase-IN-36 retains activity against Rifampicin (HY-B0272) -resistant M. tuberculosis[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial; Carbonic Anhydrase
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=S(C(C=C1)=CC=C1N/N=C/C(C=C2)=CC=C2N(C=C3)N=C3C4=CC5=CC=CC=C5O4)(N)=O
Molecular Formula
C24H19N5O3S
Molecular Weight
457.50
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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