BChE-IN-45
BChE-IN-45 is a competitive (cholinesterase) dual acting inhibitor (Ki = 11.13 μM) . BChE-IN-45 has an IC50 of 13.8 μM for BChE and 35.63 μM for AChE. BChE-IN-45 can be used for research on Alzheimer's disease[1].
Product Specifications
CAS Number
425611-45-6
UNSPSC
12352005
Target
Cholinesterase (ChE)
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
CC1=CC=C(COC2=CC=C(C3C(C(CC(C)(C)C4)=O)=C4NC(CC(C)(C)C5)=C3C5=O)C=C2OC)C=C1
Molecular Formula
C32H37NO4
Molecular Weight
499.64
References & Citations
[1]Najafi Z, et al. Novel Hexahydroacridine‐1, 8‐diones as Cholinesterase Inhibitors: Design, Synthesis, Molecular Docking, and Molecular Dynamics Simulation[J]. ChemistrySelect, 2025, 10 (39) : e00879.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE
Frequently Asked Questions
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