AB19
AB19 is a potent Vav1 inhibitor. AB19 inhibits Vav1 and reduces its downstream ERK phosphorylation. AB19 shows anti-proliferative activity in pancreatic cancer models. AB19 can be used for pancreatic cancer research[1].
Product Specifications
UNSPSC
12352005
Target
ERK
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Field of Research
Cancer
Smiles
CCCCCCCCCCCCCC[N+]1=CC=C(OCC(C/C2=C(C)\C)(CO)OC2=O)C=C1.[Br-]
Molecular Formula
C28H46BrNO4
Molecular Weight
540.57
References & Citations
[1]Bellomo A, et al. Novel DAG-Lactone-Based Vav1 Inhibitors Show Anti-proliferative Activity in Pancreatic Cancer Models. ChemMedChem. 2025 Oct 20:e202500589.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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