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AB19

AB19 is a potent Vav1 inhibitor. AB19 inhibits Vav1 and reduces its downstream ERK phosphorylation. AB19 shows anti-proliferative activity in pancreatic cancer models. AB19 can be used for pancreatic cancer research[1].

Product Specifications

UNSPSC

12352005

Target

ERK

Related Pathways

MAPK/ERK Pathway; Stem Cell/Wnt

Field of Research

Cancer

Smiles

CCCCCCCCCCCCCC[N+]1=CC=C(OCC(C/C2=C(C)\C)(CO)OC2=O)C=C1.[Br-]

Molecular Formula

C28H46BrNO4

Molecular Weight

540.57

References & Citations

[1]Bellomo A, et al. Novel DAG-Lactone-Based Vav1 Inhibitors Show Anti-proliferative Activity in Pancreatic Cancer Models. ChemMedChem. 2025 Oct 20:e202500589.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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