Antimalarial agent 53
Antimalarial agent 53 is an antimalarial agent. Antimalarial agent 53 blocks protein synthesis by inhibiting the cytoplasmic ribosomes of malaria parasites, exhibiting potent antimalarial activity (IC50 = 3.9 nM) and good selectivity. Antimalarial agent 53 has no cross resistance and good safety. Antimalarial agent 53 can be used for research on malaria[1].
Product Specifications
UNSPSC
12352005
Target
Parasite
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(NC1=CC(NN2CCN(C)CC2)=CC=C1O)C3=CC(OC4=CC(C(F)(F)F)=CC=N4)=CC=C3
Molecular Formula
C24H24F3N5O3
Molecular Weight
487.47
References & Citations
[1]Bravo P, et al. A Novel Antimalarial Agent that Inhibits Protein Synthesis in Plasmodium falciparum. Angew Chem Int Ed Engl. 2025 Oct 20:e202514085.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-179118/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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