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VU0519975

VU0519975 is a raft destabilizing compound. VU0519975 reduces PMP22 raft partitioning and destabilizes ordered domains. VU0519975 significantly decreases the fraction of phase separated GPMVs[1].

Product Specifications

CAS Number

[1357850-32-8]

UNSPSC

12352005

Target

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Smiles

CC1=C(C=CC=C1NC(C2=C(NN=N2)NC3=CC=CC=C3)=O)Cl

Molecular Formula

C16H14ClN5O

Molecular Weight

327.77

References & Citations

[1]Stefanski KM, et al. Pharmacological Tools to Modulate Ordered Membrane Domains and Order-Dependent Protein Function. bioRxiv [Preprint]. 2025 Oct 4:2025.10.03.680351.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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